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Estrogen therapy is linked to fewer signs of Alzheimer’s in the brain

Women who used estrogen-only hormone therapy had less severe Alzheimer’s pathology at autopsy

A older woman reads the directions on estrogen or hormone therapy.

Women on estrogen-only hormone therapy show fewer plaques and protein tangles, signature signs of Alzheimer’s disease in the brain.

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By Nora Bradford

Women are about twice as likely to get Alzheimer’s disease as men. But women who take estrogen as hormone therapy after menopause have fewer telltale neurological signs of Alzheimer’s disease after death than women who don’t, scientists report August 12 in Neurology.