News

Gene defect leads to warts and more

By
11:20am, October 23, 2001

From San Diego, at a meeting of the American Society of Human Genetics

To attract immune cells to infection, the body uses signals called chemokines. Like noses on bloodhounds, chemokine receptors on immune cells sniff for chemical cues, in this case, chemokines in blood.

Researchers have for the first time associated a disease with mutations in a gene for one of these receptors. People with a rare disorder known as WHIM syndrome suffer warts and recurrent bacterial infections. The patients have normal immune cells, but the cells seem to have trouble moving out from their home in bone marrow toward an infection, says George A. Diaz of the Mount Sinai School of Medicine in New York.

This article is available only to subscribing members. Join SSP today or Log in.

More from Science News