Eighteen researchers, including two CRISPR pioneers, are calling for a temporary ban on creating gene-edited babies.
“We call for a global moratorium on all clinical uses of human germline editing — that is, changing heritable DNA (in sperm, eggs or embryos) to make genetically modified children,” the statement’s cosigners, who come from seven countries, wrote in the March 14 Nature.
Among the document’s signatories are CRISPR pioneers Feng Zhang of the Broad Institute of MIT and Harvard University and Emmanuelle Charpentier of the Max Planck Unit for the Science of Pathogens in Berlin.
The proposed moratorium would last about five years to give time for public education and debate about experiments. The delay would buy time for scientists to further test and refine CRISPR/Cas9 and other gene-editing tools to make them safer. The moratorium would also be voluntary, with each country pledging individually not to allow clinical trials for creating gene-edited children. Countries would make independent decisions on how long such a ban should last.