Experimental herpes vaccine works in mice | Science News

Be a Champion for Science

Get your subscription to

Science News when you join.

News in Brief

Experimental herpes vaccine works in mice

Shot takes different tack from previous strategies

3:04pm, March 10, 2015

TAKING OVER  This electron microscope image of an infected cell shows production of herpes simplex virus particles (green/yellow). An experimental herpes vaccine stops herpes in its tracks in mice.

A test vaccine against genital herpes shows full protection against the live virus in mice, researchers report March 10 in eLIFE.

Previous herpes vaccine candidates contained a viral protein called gD-2, an obvious component since it is needed for herpes to invade cells and would therefore elicit an immune reaction. Such experimental vaccines succeeded in guinea pigs, but they failed in people. Researchers at Albert Einstein College of Medicine in New York City wondered if having a gD-2 component in a vaccine might “mask” other viral particles and allow them to escape immune detection.

This article is available only to subscribing members. Join the Society today or Log in.

Get Science News headlines by e-mail.

More Immune Science articles