Finding immune cells that stop a body from attacking itself wins medicine Nobel

The 2025 prize goes to 3 researchers who ID’d T-regs and their role in autoimmune disease

Line sketches of the three winners of the 2025 Nobel Prize in physiology and medicine from left to right: Mary Brunkow, Fred Ramsdell, Shimon Sakaguchi, The trio won for discovering a type of immune cell.

Mary Brunkow (left), Fred Ramsdell (middle) and Shimon Sakaguchi (right) have won the Nobel Prize in physiology or medicine for discovering regulatory T cells, which keep the immune system from attacking the body.

Niklas Elmehed © Nobel Prize Outreach

Work on peacemakers in the immune system won the 2025 Nobel Prize in physiology or medicine.