Shutting Off an On Switch: Novel drugs slow two cancers in mice
By Nathan Seppa
One way to arrest cancer is to identify a molecule that malignant cells just can’t do without—and then disable it. Researchers now report success with two experimental drugs that target such a protein, which triggers rapid growth and other malignant changes in cancer cells.
In mice, one of the drugs slows multiple myeloma, a lethal bone marrow cancer, and the other limits fibrosarcoma, a tumor of fibrous tissues. The scientists report their findings in two articles in an upcoming Cancer Cell.