Fragment foils Alzheimer's protein | Science News



Support credible science journalism.

Subscribe to Science News today.


Fragment foils Alzheimer's protein

12:15pm, March 7, 2006

Chemists have synthesized a protein fragment that, in test-tube studies, disrupts the formation of the fiber networks suspected to be a cause of Alzheimer's disease.

In the brains of Alzheimer's patients, a protein called beta-amyloid assembles into fibers, which clump together to create networks of fibers called plaques. In the first step toward this fiber formation, the stringlike proteins bind along their sub-nanometer lengths, says Robert P. Hammer of Louisiana State University in Baton Rouge. The resulting sheets of protein organize into micrometer-scale fibers.

This article is available only to subscribing members. Join the Society today or Log in.

Get Science News headlines by e-mail.

More from this issue of Science News

From the Nature Index Paid Content