Deciphering a person’s genetic instruction book doesn’t predict medical future
CHICAGO — The human genetic instruction book is as lousy at predicting disease as an almanac is at predicting the weather, a prominent cancer researcher concludes from an analysis of the genetic data from thousands of pairs of identical twins.
A technological revolution has made deciphering genetic instruction books, called genomes, quicker and cheaper than ever before. Many scientists have touted the genome as a crystal ball for peering into people’s medical futures. But Bert Vogelstein of Johns Hopkins University School of Medicine wondered just how informative knowing a person’s genetic makeup could be.