Rare variants hurt ability to detect, fight viruses
COLD SPRING HARBOR, N.Y. — A faulty virus-sensing gene can make the common cold or respiratory syncytial virus deadly for babies and toddlers, a new study suggests.
Almost all children catch those viruses by age 2 or 3 years. Most kids quickly clear the viruses, but about one in 1,000 are admitted to the intensive care unit with severe pneumonia. The reason some tykes get really sick is in their genes, Samira Asgari, a computational biologist at the Swiss Federal Institute of Technology in Lausanne reported May 12 at the Biology of Genomes conference.