Your article made a common mistake in characterizing the mechanism of steroid-hormone receptors. These receptors are not “proteins on the cell surface” but rather, and uniquely, positioned intracellularly. Steroid hormones pass directly from the bloodstream to the cytoplasm, where they induce changes in the receptor proteins, enable movement into the nucleus, and activate specific genes.

Mac Black
Seattle, Wash.

From the Nature Index

Paid Content