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50 Years Ago

50 years ago, doctors lamented a dearth of organ donors

Excerpt from the March 15, 1969 issue of Science News

By
6:00am, March 12, 2019
doctor carrying donor organ

DISHEARTENING  Fifty years ago, a low supply of donor organs meant a grim future for patients in need of a working heart.

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Cover of the March 15,1969 issue of Science New
Number of donors drops —

Both laymen and surgeons have become faint-hearted about heart transplants.… The rejection and infection problems remain unsolved, and although Dr. [Denton A.] Cooley has performed the greatest number of transplants in the world, he has had to stop operating for lack of donors. — Science News, March 15, 1969

Update

Candidates for heart or other organ transplants still far outnumber donors. Every day, 20 people on average die while waiting for a transplant in the United States. Scientists hope to remedy the shortage using organs harvested from animals. To keep a human body from rejecting nonhuman cells, scientists are turning to gene editing (SN: 10/14/17, p. 26). So far, baboons given genetically modified pig hearts have survived for about six months (SN Online: 12/5/18). Others are growing organs, creating a sterilized scaffold from an animal or cadaver organ and repopulating the scaffold with the organ recipient’s cells (SN: 5/18/13, p. 14). Pigs have survived several weeks after being implanted with lab-grown lungs (SN: 9/15/18, p. 8).

Citations

Staff. Number of donors drops. Science News. Vol. 95, March 15, 1969, p. 259. 

Further Reading

J. Leman. Baboons survive 6 months after getting a pig heart transplant. Science News Online. December 5, 2018. 

M. Temming. Scientists successfully transplant lab-grown lungs into pigsScience News. Vol. 194, September 15, 2018, p. 8.

A. Witze. Luhan Yang strives to make pig organs safe for human transplantsScience News. Vol. 192, October 14, 2017, p. 26.

N. Seppa. Bioengineered kidney transplanted into ratScience News. Vol. 183, May 18, 2013, p. 14.

A. Goho. Body buildersScience News. Vol. 165, March 6, 2004, p. 155.

J. Travis. The Xeno-solutionScience News. Vol. 148, November 4, 1995, p. 298.

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