Year in review: ‘Three-parent baby’ technique raises hope and concern

Safety and ethical questions surround controversial mitochondrial replacement therapy


SPINDLE SWAP  A boy born in April has DNA from mom and dad, as well as mitochondria from a female donor. To make "three-parent" embryos, the chromosome-containing spindle, shown at the tip of the pipette, is removed from a woman's egg and inserted into a donor egg.

Center for Embryonic Cell and Gene Therapy/Oregon Health & Science Univ.

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