Year in review: ‘Three-parent baby’ technique raises hope and concern
Safety and ethical questions surround controversial mitochondrial replacement therapy

SPINDLE SWAP A boy born in April has DNA from mom and dad, as well as mitochondria from a female donor. To make "three-parent" embryos, the chromosome-containing spindle, shown at the tip of the pipette, is removed from a woman's egg and inserted into a donor egg.
Center for Embryonic Cell and Gene Therapy/Oregon Health & Science Univ.
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