Two front-runners show promising results
The race to develop Ebola vaccines closed in on the finish line this year, as scientists tested two candidates that could ultimately be stockpiled for future outbreaks. Both vaccines target a protein made by Zaire ebolavirus, the virus that raged through West Africa in 2014 and early 2015, killing more than 11,000 people (SN: 12/27/14, p. 14). The epidemic now appears under control across West Africa, with only a few cases in Liberia.
One vaccine relies on a live, replicating virus to stimulate an immune response in patients. In August, researchers testing it reported results from the largest Ebola vaccine trial to date to show evidence of protection: a study of 7,651 Guinean adults. None of the people