This article raised so many questions. Do children who play in the dirt get their increased immune resistance from phages in the dirt? Is there a phage connection in the AIDS story? Does the risk of dying of heart attacks have a phage connection? If so, is group A Streptococcus involved? Do we need a new major scientific effort to identify the next million or billion phages? How are the phage populations different from the ocean to beach to city to farm to forest? The article was one of the most intriguing and provocative in recent history.

John Harden
Kirkland, Wash.