In this article researcher S. Jill James implicates low glutathione and heavy metal exposure in autism. This may be the case, but glutathione has a number of important functions that have nothing to do with heavy metal binding. As an antioxidant, glutathione reduces toxic free radicals. Glutathione is also a key factor in the maintenance of cellular redox poise. It goes without saying that it is also possible that low glutathione is correlated with, but not causative of, autism.
Todd P. SilversteinWilliamette University
Santa Barbara, Calif.