50 years ago, starving tumors of oxygen proposed as weapon in cancer fight

Excerpt from the May 4, 1968 issue of Science News

mouse breast tumor

AIR SUPPLY  Depriving some cancerous tumors, such as this mouse breast tumor, of oxygen by cutting off blood vessels (red) is one treatment approach. But some oxygen-starved cancer cells (green) can become more aggressive.

Steve Seung-Young Lee/Univ. of Chicago Comprehensive Cancer Center, NCI/NIH, Flickr (CC By-NC 2.0)

Starve the tumor, not the cell

Animal experiments demonstrate for the first time that transplanted tumors release a chemical into the host’s bloodstream that causes the host to produce blood vessels to supply the tumor.…