Inked mice hint at how tattoos persist in people

Immune cells pass pigment from one generation to the next

tattoo

TAIL TATS  When researchers tattooed mouse tails, the only cells found with ink inside were macrophages. The tattoo appeared the same before (left) and after (right) ink-holding macrophages were killed, because it was recaptured by new macrophages.

A. Baranska et al/J. Expt. Med. 2018

Tattoos may have staying power because of a hand off between generations of immune cells known as macrophages, say a group of French researchers.