Predicting Parkinson’s

Researchers search for early warnings in the brain

By Carolyn Gramling

A HEAVY LOAD. Carol McLeod’s self-portrait expresses the burden of her everyday life while battling Parkinson’s disease. McLeod
ALTERED STATES. These positron-emission tomography images show brain areas with unusual metabolic activity in a Parkinson’s disease patient. Side view (left) shows that regions that coordinate physical movement are red, indicating overactivity when compared with normal metabolism.