As I read this article, I was wondering whether the findings discussed suggest that a woman who has had both a hysterectomy and an oophorectomy should be on estrogen hormone therapy. Does a woman with no uterus or ovaries produce enough estrogen in other organs to benefit from the estrogen receptor beta?

Cathy Gregor
Alexandria, Va.

Almost all estrogen in a premenopausal woman’s body is produced by the ovaries.