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Brain gene is tied to obesity

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10:34am, January 7, 2004

Researchers studying the DNA of people in Finland and Sweden have amassed evidence that a gene involved in brain chemistry influences whether a person is thin or fat.

Few specific genes have been convincingly linked to human obesity. A research team headed by Päivi Pajukanta of the University of California, Los Angeles now points the finger at one called solute carrier family 6 member 14 (SLC6A14).

The investigators originally studied obese and thin siblings within a group of Finnish families.

They found evidence that a region on the X chromosome might account for some of the weight differences. Within that region were several genes, including SLC6A14.

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