Circadian clockwork takes unexpected turns

One group of neurons follow a different pattern than others that guide the brain’s master clock

On the television show “24” a silent countdown usually means a character has died. But for some cells in the brain’s time-keeping center, silent running is part of life.

Cells in the suprachiasmatic nuclei, a tiny group of neurons in the hypothalamus, serve as a master clock to regulate the body’s circadian rhythms — daily fluctuations in hormone release, body temperature, blood pressure and other processes — and help set meal and bed times.