Connectivity may play role in autism

Genome-wide associations home in on proteins responsible for cell adhesion

In autism, connections are important, new research suggests. Three genetic studies attempting to understand the disorder’s development point to molecules that form and maintain connections between cells.

“Of all the 20,000-plus genes [in the human genome], we’re down to a small family that keeps getting implicated,” says Thomas Insel, director of the National Institute of Mental Health, in Bethesda, Md.