A lack of sleep can induce anxiety | Science News



Help us keep you informed.

Support Science News.

News in Brief

A lack of sleep can induce anxiety

Brain activity is altered in people spending the night awake

11:51am, November 6, 2018
sleepless woman

TOSSING AND TURNING  A sleepless night led to higher anxiety levels in healthy people, as well as brain changes that mirrored those in people with anxiety disorders.

Sponsor Message

SAN DIEGO — A sleepless night can leave the brain spinning with anxiety the next day.

In healthy adults, overnight sleep deprivation triggered anxiety the next morning, along with altered brain activity patterns, scientists reported November 4 at the annual meeting of the Society for Neuroscience.

People with anxiety disorders often have trouble sleeping. The new results uncover the reverse effect — that poor sleep can induce anxiety. The study shows that “this is a two-way interaction,” says Clifford Saper, a sleep researcher at Harvard Medical School and Beth Israel Deaconess Medical Center in Boston who wasn’t involved in the study. “The sleep loss makes the anxiety worse, which in turn makes it harder to sleep.”

Sleep researchers Eti Ben Simon and Matthew Walker, both of the University of California, Berkeley, studied the anxiety levels of 18 healthy people. Following either a night of sleep or a night of staying awake, these people took anxiety tests the next morning. After sleep deprivation, anxiety levels in these healthy people were 30 percent higher than when they had slept. On average, the anxiety scores reached levels seen in people with anxiety disorders, Ben Simon said November 5 in a news briefing.

What’s more, sleep-deprived people’s brain activity changed. In response to emotional videos, brain areas involved in emotions were more active, and the prefrontal cortex, an area that can put the brakes on anxiety, was less active, functional MRI scans showed.

The results suggest that poor sleep “is more than just a symptom” of anxiety, but in some cases, may be a cause, Ben Simon said.


E. Ben Simon and M.P. Walker. Underslept and overanxious: The neural correlates of sleep loss-induced anxiety in the human brain. Society for Neuroscience Annual Meeting, San Diego, November 4, 2018.

Further Reading

B. Brookshire. To beat sleepiness of anxiety drugs, team looks to body’s clock. Science News Online, January 14, 2015.

Get Science News headlines by e-mail.

More from Science News

From the Nature Index Paid Content