Mutation effects often depend on genetic milieu

Other genes at least as important as environment, study shows

3:41pm, April 13, 2010

The genetic differences that make each individual unique may be even more important than scientists previously thought, a new study of fruit flies suggests.

In two strains of the fruit fly Drosophila melanogaster, underlying genetic makeup outweighs any other factor in dictating how a specific mutation will affect wing shape, geneticists Sudarshan Chari and Ian Dworkin of Michigan State University in East Lansing reported in Washington, D.C., April 8 at the 51st Annual Drosophila Research Conference.

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