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Mutation effects often depend on genetic milieu

Other genes at least as important as environment, study shows

The genetic differences that make each individual unique may be even more important than scientists previously thought, a new study of fruit flies suggests.

In two strains of the fruit fly Drosophila melanogaster, underlying genetic makeup outweighs any other factor in dictating how a specific mutation will affect wing shape, geneticists Sudarshan Chari and Ian Dworkin of Michigan State University in East Lansing reported in Washington, D.C., April 8 at the 51st Annual Drosophila Research Conference.

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