These medical breakthroughs and advances gave patients new hope in 2025

Notable results include a Huntington’s treatment and custom gene therapy

A smily chubby-cheeked baby is sitting in a rainbow striped cloth baby seat. His two sisters and brother sit around him. Everyone is smiling.

A gene therapy designed just for baby KJ Muldoon (center, surrounded by his siblings) saved his life.

CHOP

American science took a beating this year, with cuts to funding, jobs and credibility. And yet, scientists persisted and made progress. These advances in 2025 spotlight how crucial it is to support biomedical research — and how much of an impact it can have on people’s lives.