Cutting off a brain enzyme reversed Alzheimer’s plaques in mice

Nerve cell‒damaging clumps vanished, but enzyme may be key for other brain functions

Alzheimer's protein

VANISHING ACT  Globs of a protein linked to Alzheimer’s (red) dot a brain sample from a 10-month-old mouse (left). But these disease hallmarks largely vanish in a similar mouse that mostly lacks a particular brain enzyme.

X. Hu et al/JEM 2018

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