Science Visualized Genetics

Genetic switch wipes out tumors in mice

Crucial gene stunts cell growth, halts progression to colon cancer

mouse cells

CELLS GONE WILD  Turning off the gene Apc in mouse intestinal cells in a culture dish spurs out-of-control cell growth (left panel, pink). Turning the gene back on restrains growth and lets the cells develop into normal intestinal tissue (green). 

K.P. O’Rourke

By Meghan Rosen

- More than 2 years ago

The gene Apc is like a club bouncer: It keeps cellular parties from growing out of control.