Gut bacteria transform compound into artery hardener
Drop that hamburger, put down the can of Monster Energy and back away from the body building pills.
A nutrient found in red meat and added to energy drinks and supplements may crank up people’s risk of heart disease, a new study suggests. Bacteria in the gut digest the nutrient, L-carnitine, and help turn it into an artery-hardening chemical — particularly in meat eaters, researchers report April 7 in Nature Medicine.
The intestinal microbes of vegetarians and vegans didn’t make much of the chemical, even when researchers fed them an 8-ounce sirloin steak.
“I always thought that what I ate mattered, but I never realized that my gut bacteria might matter more,” says biochemist Harry Ischiropoulos of the University of Pennsylvania in Philadelphia, who was not involved with the study.
What’s more, high blood levels of the bacterial by-product of L-carnitine, called trimethylamine N-oxide or TMAO, were an