Mouse method turns skin cells to stem cells

Scientists have reprogrammed mouse skin cells to mimic embryonic stem cells that can morph into any type of cell in the body.

MIGHTY RARE MOUSE. This mouse was produced from reprogrammed skin stem cells that acted like embryonic stem cells. S. Ogden/Whitehead Institute

Last year, Shinya Yamanaka and his team at Kyoto University in Japan found that they could insert into skin fibroblast cells active copies of four genes earlier identified as essential to a stem cell’s pluripotency—the ability to turn into any cell.