Nerve cell miswiring linked to depression

Mouse study identifies gene needed for proper assembly of serotonin circuitry

mouse brain

ALL TANGLED UP  In a healthy mouse (left), nerve cells (white) that release serotonin extend through the hippocampus. But when a specific gene is knocked out, those nerve cell wires clump together (right).

T. Maniatis/Columbia's Zuckerman Institute

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