Cells have molecule for protein triage

Cells produce bad proteins all the time, and in large-enough numbers, these molecules can spell danger for the body. When misfolded or unfolded, proteins can’t do their jobs. At worst, they harm cells by clumping into the sticky plaques that are the signatures for neurodegenerative disorders such as Alzheimer’s disease.

A clear understanding of how most cells successfully manage protein repair and disposal has been elusive.