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Crosses make lab mice even more useful

New strains of lab animals bred to better pinpoint the genetic roots of disease

5:54pm, February 17, 2012

Scientists have built a better mouse. But rest easy — these mice don’t require improved traps.

The new mice may give scientists an advantage in tracing genetic sources of common diseases and investigating interactions between genes and environmental factors. In a series of 15 papers published in the February issues of Genetics and G3: Genes, Genomes, Genetics, researchers describe the creation of the new-and-improved mice, known as the Collaborative Cross strains, and some of the ways scientists may use the mice in medical studies.

Biomedical researchers use inbred strains of

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