Men who lose Y chromosome have high risk of cancer

Genetic defect in blood cells also associated with shorter life span

illustration of X and Y chromosomes

SMALL BUT MIGHTY  The Y chromosome (blue in an illustration) is far smaller than the X chromosome (green) and contains few genes, but its loss may spell big trouble for men. Men whose blood cells have jettisoned the chromosome have a higher risk of cancer and may have shorter life spans.

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SAN DIEGO — Losing the Y chromosome in blood cells may bring on cancer and shorten men’s lives, new research suggests.