Newly identified brain circuit hints at how fear memories are made

Working with rats, researchers reveal the shifting neural circuitry behind the recall of unpleasant experiences

SHIFTING CIRCUITS  In rats, a fear memory is initially recalled through brain cell connections between the prefrontal cortex (PL) and the basolateral amygdala (BLA). A week later, the circuit to recall the same memory shifts, relying on neurons in the paraventricular nucleus of the thalamus (PVT) that connect to the central amygdala (CeA).

Gregory Quirk/Univ. of Puerto Rico School of Medicine

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