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IVF kids show shift in gene activity

Team finds differences related to metabolism and growth

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2:49pm, February 21, 2010

SAN DIEGO — Some genes in children conceived with in vitro fertilization differ in activity levels compared with other children, recent studies show.

 In the most recent work, researchers found substantial differences in activity of dozens of genes of interest, epigenetics researcher Carmen Sapienza of Temple University Medical School in Philadelphia reported February 21 at the annual meeting of the American Association for the Advancement of Science.

With IVF in general, “we’re kind of doing an experiment here,” Sapienza said. “By and large, the kids are fine … but if there are [differences] you can measure, then you should.”

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