Team finds differences related to metabolism and growth
SAN DIEGO — Some genes in children conceived with in vitro fertilization differ in activity levels compared with other children, recent studies show.In the most recent work, researchers found substantial differences in activity of dozens of genes of interest, epigenetics researcher Carmen Sapienza of Temple University Medical School in Philadelphia reported February 21 at the annual meeting of the American Association for the Advancement of Science.
With IVF in general, “we’re kind of doing an experiment here,” Sapienza said. “By and large, the kids are fine … but if there are [differences] you can measure, then you should.”
Epidemiological studies have revealed a greater incidence of low birth weight in children conceived with IVF. Among other health issues, low birth weight is a risk factor for obesity, hypertension and type 2 diabetes later in life.
In the Oct. 15 Human Mo