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SARS Control: First nasal vaccine effective in monkeys

Inhaling a new experimental vaccine may offer protection against severe acute respiratory syndrome, or SARS. The vaccine, tested in African green monkeys, is the first to be administered directly to the respiratory tract and is also the first that confers immunity with a single dose.

"This could be used for local outbreak control," says Peter L. Collins of the National Institute for Allergy and Infectious Diseases in Bethesda, Md. "It would be the most rapid way to vaccinate those at risk for SARS," especially vulnerable health care workers, he says. SARS became a health crisis in 2003. To date, it has infected more than 8,000 people worldwide, killing 774.

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