Sometimes an antibiotic is much more

For years, tetracyclines have proved invaluable as a family of everyday antibiotics. Now, a therapeutic alter ego for these drugs is emerging–one unrelated to their germ-fighting prowess.

Treatment with a tetracycline prevented in a diabetic rat’s eye (top) a cataract such as that shown (arrow) in an untreated diabetic animal’s eye (bottom). SUNYStony Brook

At the American Association for the Advancement of Science (AAAS) annual meeting in San Francisco last week, scientists reported using tetracyclines to thwart a variety of diseases including periodontal bone loss and cancer.