Injections gin up antibodies that limit drug's effects, study in mice shows
Antibodies generated by a new vaccine can capture molecules of cocaine in the precious few seconds that lapse before the drug reaches the brain, a study in mice shows. Although the antibody brigade doesn’t snag all the cocaine, it seems to collar enough to greatly subdue the agitation that mice exhibit when given the drug.
Based on these findings, the researchers are moving on to studies in rats and monkeys in hopes of testing the vaccine in people. The new report will appear in the March Molecular Therapy.