Angiostatin testing in people begins | Science News



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Angiostatin testing in people begins

12:23pm, June 5, 2001

A drug that cured cancer in mice has been proved safe in people. Nineteen patients with various cancers received daily intravenous infusions of the drug angiostatin for up to 6 months without showing any serious side effects, says study coauthor Robert L. Capizzi, an oncologist at Thomas Jefferson Medical College in Philadelphia. Before the test, all the patients had failed to improve during chemotherapy.

Researchers and the public are closely watching angiostatin's progress. In laboratory animals, it prevents a tumor from creating a system of blood vessels through which to get nutrients.

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