Compounds pass the smell test

A vile-smelling but versatile class of compounds may find a role in more chemistry laboratories with the introduction of easily made, inoffensive versions.

Isonitriles, chemicals characterized by a triple bond between a carbon and a nitrogen atom, are useful in many reactions. But many chemists have shunned them because of their pungency, says Michael C. Pirrung of the University of California, Riverside.