A simple way to steer atoms to a difficult-to-reach position on an aromatic ring opens new possibilities
Few roads lead to meta, much to the chagrin of organic chemists trying to build compounds of particular shapes. Now researchers have found a simple way of getting molecules into the coveted meta position on an aromatic ring. The discovery, reported in the March 20 Science, opens the door to a flood of research that could yield products from new drugs to electronic materials, scientists say.
The find “combines new chemistry and recent developments with a very old problem,” says Robert Maleczka Jr. of Michigan State University in East Lans