News Genetics

Mice can be male without Y chromosome

Genetic manipulations enable female embryo to develop as opposite sex, study shows

mice

MADE MALE  This male mouse (white) has no Y chromosome, but was able to father pups (brown) when scientists injected his immature sperm into eggs. Researchers made the mouse male by manipulating genes on other chromosomes. 

Yasuhiro Yamauchi

By Tina Hesman Saey

- More than 2 years ago

Researchers have created male mice with no trace of a Y chromosome, supposedly the defining hallmark of being male.