How to rewire the eye

Transforming nerve cells into light-sensing cells aims to restore sight in some blind patients

optogenetics

SEEING THE LIGHT  The brain’s window on the visual world is a multilayered tissue at the back of the eye called the retina. Light-detecting rods and cones sit at the very back of the tissue. They pass information to the brain via bipolar cells and ganglion cells. Humans and some animals have sharp vision thanks to the fovea, a window in the retina that offers direct access to the cones.

Eye: Tony Graham/Getty Images, adapted by J. Hirshfeld; webvision.med.utah.edu, adapted by J. Hirshfeld

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