Normal 0 false false false MicrosoftInternetExplorer4 One of the molecular players in breast cancer arising from an inherited mutation has a surprising role in squelching tumors, researchers report in the Oct. 10 Molecular Cell.
In some types of cancer cells, researchers have shown that a gene called SIRT1 acts to keep cells alive longer, which leads to more tumor growth. But SIRT1 actually inhibits tumor growth in breast cancers caused by specific mutations in the BRCA1 gene, the new research shows.