Medication helps brain clear plaque-forming protein
A cancer drug that sweeps an ominous plaque-forming protein from mouse brains within hours and reverses Alzheimer’s-like behavior in the rodents in days may offer a powerful new way to prevent or even reverse the brain-wasting disease in humans.
The drug, called bexarotene, has been on the market for about 10 years to treat T-cell lymphoma, often after other treatments have failed. But bexarotene can do a completely different job in the brain, researchers report online February 9 in Science.
“This is a pretty fantastic drug,” says Paige Cramer of Case West