As cells age, the nucleus lets the bad guys in

Stable pore proteins in nuclear membrane stick around but also weaken

As cells get older, they don’t lose their hair or teeth. Instead, they lose control over their nuclear membrane, the protective barrier that encases DNA in the nucleus, concludes a study published in the Jan. 23 Cell. This age-dependent leakiness may be closely tied to cell deterioration and age-related diseases such as Parkinson’s and Alzheimer’s, the new work suggests.