DNA flaws can stack up as cancer grows | Science News



Support credible science journalism.

Subscribe to Science News today.


DNA flaws can stack up as cancer grows

Acute myeloid leukemia appears to progress by accumulating mutations

1:01pm, March 29, 2011

VANCOUVER — As a man’s cells grew cancerous, a wide range of mutations gradually emerged too, a new gene sequencing study finds. The results provide a deep understanding of the genetic changes that allowed an aggressive form of leukemia to set in and take hold in one patient, Elaine Mardis of Washington University in St. Louis said in a March 28 presentation at the annual conference on Research in Computational Molecular Biology.

“Cancers’ origins lie in the genome,” Mardis said. “These genetic approaches are really addressing the underlying questions of cancer biology.”

This article is available only to subscribing members. Join the Society today or Log in.

Get Science News headlines by e-mail.

More from Science News

From the Nature Index Paid Content